Searchable abstracts of presentations at key conferences in endocrinology

ea0016p331 | Endocrine tumours | ECE2008

Novel MEN1 germline mutations and clinical features in Greek patients with multiple endocrine neoplasia type 1

Peppa Melpomeni , Pikounis Vasilios , Kamakari Smaragda , Peros George , Economopoulos Theofanis , Raptis Sotirios A , Hadjidakis Dimitrios

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant hereditary disorder, associated with mutations of the MEN1 gene, characterised by the combined occurrence of tumours of the parathyroid glands, the pancreatic islet cells and the anterior pituitary.Aim: To identify MEN1 gene mutations and characterize clinical manifestations in Greek patients with MEN1.Patients and methods: We studied 4 ...